http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-528480-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-36 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-40 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-092 |
| filingDate | 1963-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1ad96abf4c880c927bec04ccbaf780f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8c97333282dd5507821fa977a8c8661 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b2581e7232832a95ef6a4768e0f622e |
| publicationDate | 1972-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-528480-A |
| titleOfInvention | Process for the preparation of alkanolamine derivatives |
| abstract | Alkanolamines - (I) where Y = O - R1, R3, R4 = H - (R2 = Et - (B = 4-Cl-3-Me-phenyl; 3,5-Me2-phenyl - (R2 = n-Pr - (B = 3-tolyl; 3,5-Me2-phenyl; 2,5-Cl2-phenyl; 3-MeO-phenyl - or Y = O R1 = H, opt. substd. alkyl, alkenyl, aralkyl - R3, R4 = H, alkyl - R2 = branched alkyl, substd. alkyl, cycloalkyl alkenyl, opt. substd. ( >7C) aralkyl - B = phenyl substd. at 3 or 4 only, or is substd. at 2 only by: iodine, HO, NO2, acyl, aryl, aryloxy, alkylaryloxy, arylthio, arylsulphonyl, arylamino, aralkyl, aralkoxy; or it is substd. by up to 5 substituents, - or Y = S R1 = H R3, R4 = H, alkyl - R2 = H, alkyl, cycloalkyl, alkenyl, aralkyl - B = substd. phenyl - together with their esters and salts, but excluding the following 1-(substd. phenoxy)-3-(substd. amino)-2-propanols:- - 1- 4-Cl3- 1-Me-2-Ph-ethyl; cyclohexyl; - isoamyl - 2,6-Me2 isopropyl - 4-t-amylisobutyl; isoamyl; isopropyl - 4-t-butyl isoamyl - 2-MeO isobutyl; N-isopropyl-N-Me. - beta-Adrenergic blockers, useful in the treatment of coronary arterial disease. - A mixt. of 1-Cl-3-(2,3-Me2-phenoxy)-2-propanol (II) (2.03 pts.) and isopropylamine (15 pts.) is heated at 70-80 deg. for 10 hrs - Working up gives 1-(2,3-Me2-phenoxy)-3-isopropylamino-2-propanol, m.p. 110-2 deg. (petrol). |
| priorityDate | 1963-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.