abstract |
New cpds. of formula:- (where Z = O, H2 or H(OH); Y = O or S; X = the gp. -ANRR' or the gp. A = 2-8C alkylene; R and R' = H, lower alkyl, 3-6C cycloalkyl, 3-6C alkenyl or R and R' + N =pyrrolidine, piperidine, N-alkyl piperazine or morpholine; n = 0-2; m = 1 or 2; R2 = H, lower alkyl, 3-6C alkenyl) including their acid addn. salts have antiviral activity and may be administered, parenterally orally or topically in pharmaceutical compositions together with the usual carriers. |