| abstract |
5-(2-Methylene)alkanoyl-2,3-dihydro-benzo-furan and -thiophene-2-carboxylic acids prepn. Cpds. (I) useful as diuretics and saluretics: (where R is 1-6C alkyl; X is O or S; Y1 and Y2 are H or Me; Z1 and Z2 are H, Cl, Br, I, Me, Et, MeO or EtO) are prepd. by hydrolysing a cpd. (II) or (III): (where Am is a tertiary amino gp. and R1 is 1-10C alkyl or 5-7C cycloalkyl). |