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filingDate 1967-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1972-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-522592-A
titleOfInvention Process for the preparation of therapeutically active hydroxycyclohexanecarboxylic acid esters
abstract (A)2-Substituted 2-hydroxy cyclohexane carboxylic acids of general formula (I): - X = -COOR' or -CH2COOR'; - When X = -COOR' - R = phenyl or cyclohexyl - R' = H or - Where X = -CH2-COOR' - R = phenyl - R' = H or -CH2-CH2- - (B) Salts of (I) with inorganic- and organic acids such as HCl, H2SO4, citric, malonic or tartaric acid and the quaternary ammonium salts of the esters with an alkylhalide or with methyl-p-toluenesulphonate. - (C) Therapeutic preparations containing one or more of A and/or B together with inert fillers and/or therapeutically active compounds. - (I) have choleretic- and antispastic activity; they have no hypotensive activity and are esp. suitable for the treatment of cramp in the gall ducts and bowels. They are therefore valuable therapeutics in the treatment of various diseases of gall and liver and of spastic conditions in the metabolic system, gall ducts, urinary tract and sexual organs.
priorityDate 1966-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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