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filingDate 1968-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b135068819e9b9dd92989a1de3b1bac5
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publicationDate 1972-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-520704-A
titleOfInvention Process for the preparation of heterocyclic compounds
abstract (A) Compds. (I) and their salts:- - where Het = thiazole, isothiazole, oxazole, isoxazole, pyrrole, thiophene, furan, pyridine or pyrimidine - X = H, (1-3C) alkyl or alkoxy - Y = phenyl opt. substd. with 1 or 2 halogen or with CF3 - Z = - - CH2OR3 where R' and R2 are H or (1-3)C alkyl and R3 is H, (1-4)C alkyl, is not > 5C alkanoyl, benzoyl, carboxybenzoyl, alkanoyloxybenzoyl, is not > 12C dialkylcyclohexyloxyalkanoyl, or N-phenylcarbamoyl, or R4-R5-CR' R2-CO- where R4 is phenyl opt. substd. by 1-2 halogen or 4-CF3 and R5 is one of the radicals under "Het" plus methoxypyrimidyl. - 5-(2-Hydroxyethyl)-4-methyl-2-phenylthiazole, 3-(2-hydroxyethyl)-5-phenyl-isoxazole, and 5-(2-hydroxyethyl)-4-methy l-2-phenyloxazole are excluded. - (B) Pharmaceutical compns. contng. (I). - Antiinflammatory, analgesic, and antipyretic agents for oral or topical use. - 4-(4-Bromophenyl)-2-(2-hydroxyisopropyl)-thiazole. - 2-(4-Chlorophenyl)-5-(2-hydroxyisopropyl)-6-methylpyridine - 2-(4-Chlorophenyl)-5-(2-hydroxyethyl)thiophene.
priorityDate 1967-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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