http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-514621-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-36 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-36 |
filingDate | 1967-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3991263348441f5370ab10264c5276 |
publicationDate | 1971-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-514621-A |
titleOfInvention | Process for the preparation of 2-lower alkyl-2,3-dihydrothieno (3,2-c) quinolines |
abstract | (A) 2,3-Dihydrothieno(3, 2-c) quinolines of general formula (I): - (I) R = H or lower alkyl - (B) Pharmaceutically acceptable, non-toxic acid addition salts of (I) with organic- and inorganic acids - (I) have antipyretic and analgesic activity with very low toxicity. - To a solution of 3.7 parts 4-mercaptoquinoline in 70 parts ethanol in which 0.76 parts sodium metal is taken up, 4.0 parts allyl bromide are added and the mixture refluxed for 5 hours. After removing the precipitated sodium bromide, the filtrate is concentrated under reduced pressure and the residue extracted with chloroform. The extract is worked up and the oily residue purified by distillation under reduced pressure to give 14 parts 2-methyl-2,3-dihydrothieno (3,2-c) quinoline. |
priorityDate | 1966-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.