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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D215-36
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-36
filingDate 1967-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b3991263348441f5370ab10264c5276
publicationDate 1971-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-514621-A
titleOfInvention Process for the preparation of 2-lower alkyl-2,3-dihydrothieno (3,2-c) quinolines
abstract (A) 2,3-Dihydrothieno(3, 2-c) quinolines of general formula (I): - (I) R = H or lower alkyl - (B) Pharmaceutically acceptable, non-toxic acid addition salts of (I) with organic- and inorganic acids - (I) have antipyretic and analgesic activity with very low toxicity. - To a solution of 3.7 parts 4-mercaptoquinoline in 70 parts ethanol in which 0.76 parts sodium metal is taken up, 4.0 parts allyl bromide are added and the mixture refluxed for 5 hours. After removing the precipitated sodium bromide, the filtrate is concentrated under reduced pressure and the residue extracted with chloroform. The extract is worked up and the oily residue purified by distillation under reduced pressure to give 14 parts 2-methyl-2,3-dihydrothieno (3,2-c) quinoline.
priorityDate 1966-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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