http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-508658-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7ad58d3c0b071069a8ee0cb8c8ba2e8 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D295-16 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-16 |
filingDate | 1967-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6abf0116e8d56eefaa4cdfc3e4fc93f5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cdbea4cd488e4883c6963b8e941e7fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ac2af689d4bc4c12d2ba96ff0bea268 |
publicationDate | 1971-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-508658-A |
titleOfInvention | Process for the preparation of 5-nitrothiazole derivatives |
abstract | Compounds (I): - X = O or SO, - R', R2, R3 and R4 = H, or an aliphatic, aralkyl, or aryl residue, all opt. substd. e.g. by halogen, NO2, O alkyl, CN, CO2H, CO2 alkyl, or SO3H. - or R' + R2 and/or R3 + R4 may form a 6-membered carbocyclic ring. - Anti-protozoals, active, e.g. vs. Entamoeba histolytica and Trichomonas vaginalis. - 3-methyltetrahydro-1,4-thiazine-1,1-dioxide (50.7g.) and 2-bromo-5-nitrothiazole (41.9g.) were refluxed 7h. in dioxan (500ml.), dild. with H2O (500ml.), cooled, filtered, washed (EtOH) and dried, giving I (39.0g., 71%), m.p. 223-4 deg. (from EtOH). |
priorityDate | 1967-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 91.