http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-507894-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12cedce8d26d81271038993ba4912fe6 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C405-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C405-00 |
filingDate | 1967-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b20ebf676b4ea861c31e8644c7fcc267 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f6bf3f62a8cea84b83fa21fe4258892 |
publicationDate | 1971-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-507894-A |
titleOfInvention | Process for the preparation of 9,13-dioxo-15-chloro-prost-14-en-acid methyl ester and its homologues |
abstract | Preparation of 9,15-dihydroxy-prostene-(13)-acid (11-desoxyprostaglandin) and its homologues, (I) where n = integer from 1 to 6 (11-desoxyprostaglandin has n = 4). The compounds show hypotensive and anti-hypertensive activity. 19 mg. Sodium borohydride is added to a solution of 44 mg. 9-hydroxy-15-oxoprostene-(13)-acid in 2.5 cc. isopropanol and the mixture is stirred at room temperature for 0.5 hr. Ether is added and the mixture is shaken three times with water. The water layer is acidified and extracted with ether. Evaporation of the ether gives 11-desoxy-prostaglandin. |
priorityDate | 1966-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 70.