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filingDate 1968-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d1a480619d9c1bd80785722ffb0c6e8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc27a85cff4b04e51337bf0e18e71449
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publicationDate 1971-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-507197-A
titleOfInvention Process for the production of new isothiocyanato-diphenylamines
abstract Active principle of anthelmintic preparations comprises isothiocyanodiphenylamines. G3A. Cpds. of formula: (in which R is hydrogen, alkyl or alkylene, with at most 3 C atoms, R1 and R3 independently of each other are hydrogen, halogen, cyano, hydroxyl, nitro, carboxyl, trifluoromethyl, alkyl, alkenyl, alkoxy, alkenyloxy, alkylathio, alkenylthio with a max. of 5C atoms, alkanoylamino, alkanoyl, alkanoyloxy, alkylthio, with a max. of 5C atoms in the alkyl. in which D is alkylene with 2 or 3 C atoms, R1 is alkylene with 1 to 3 C atoms and X is oxygen or S and R2 is hydrogen, halogen, nitro, isothiocyano or alkyl with a max. of 5C atoms, with the proviso that there is no isothiocyano ortho to hydroxy, carboxy or, when R is H, to the -NH- bridge and in the A and B benzene nuclei both para positions to an -NH- bridge can be occupied by isothiocyano groups only in the cases where R1 and/or R3 are substituents different from H, are prepared by reacting 41-aminodiphenylamines with cpds. such as thiophosgene, carbon bisulphide and phosphorus oxychloride, a pentathiodipercarbonic acid haloalkyl ester, cpds. of formula with no amino group present in the same ring as R1, R2 and R3, where These are nitro, carbonyl or trifluoromethyl, are reacted with ammonium thiocyanate or converted with benzoyl isothiocyanate to the corresponding thiourea and this decomposed. In an example, 4-chloro-41-aminodiphenylamine is stirred with thiophosgene to give 4-chloro-41-isothiocyanodiphenylamine, m.p. 110-112 degrees C.
priorityDate 1968-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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