http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-506558-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-20 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-20 |
filingDate | 1968-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bcf33aa20d3a376818206148b2027c4b |
publicationDate | 1971-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-506558-A |
titleOfInvention | Process for the preparation of cephalosporin antibiotics |
abstract | Salts of cephalosporin antibiotics of general formula I with the following amines II: trans-1,3-cyclohexanediamines (A) and their 1,4-analogues (B); trans-1,3-cyclohexane-bis-alkyleneamines (C) and their 1,4-analogues (D) in which the alkylene has up to 3C atoms; 1,3-xylene-alpha,alpha'-diamines (E) and their 1,4-analogues (F). where R = 2-thienylmethyl, 2-furylmethyl, phenylmercaptomethyl, benzyl, nitrobenzyl or CF3-phenyl-mercaptomethyl. and R' = acetoxy (cephalosporanic acid) or H (desacetoxy-cephalosporanic acid). Antibiotics of high and prolonged activity i.e. depot forms resulting from the low solubility in water. The usual Na etc. salts are soluble and when injected parenterally are assimilated and excreted in L hrs. so that 4 injections per day are required. |
priorityDate | 1968-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.