http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-506545-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3bfedd8ba4800708cecfd357707f8f67 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 1968-01-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6114ff446ac7e6f19939eddaa97d8894 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_979bf18fd4cf1c0e7aaa74250ef1106b |
| publicationDate | 1971-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-506545-A |
| titleOfInvention | Process for the preparation of antimetabolic pyrazolo (3,4-b) pyridines |
| abstract | Pyrazolo (3, 4-b) pyridines of formula (I):- where R1 = H or alkyl, preferably CH3; R2 = H or alkyl; R3 = OH, halogen, NH2, or SH. Antimetabolites of considerable interest. Inhibitors of DNA and RNA synthesis. Intermediate (II) may or may not be isolated. A mixture of 5.18g. (III; R1= C6H5CH2), 4.28g. ethyl acetoacetate, and 15ml. acetic acid was refluxed for 4 hrs., cooled, and treated with 100 ml. water to precipitate 6.58g. (I; R1=C6H5CH2, R2=CH3, R3=OH), m. 228-9 deg. |
| priorityDate | 1967-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 85.