http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-500217-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 1967-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b6501518aa9822e4d93a00de5e8872a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_540b9afd6497980b40e7a1722a04e0ee |
| publicationDate | 1970-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CH-500217-A |
| titleOfInvention | Process for the preparation of dibenzocycloheptene derivatives |
| abstract | (A) Cpds. (I) and (II) R1=H or alkyl and R2=alkyl, alkenyl, or cycloalkyl or R1 and R2 and N form a heterocyclic residue R3=H, alkyl, alkenyl or cycloalkyl R4=H, halogen, alkyl, CF3 or acyl (B) Ketals of (I) and (II) (C) Acid addn. salts of (I) and (II). CNS active anti-depressants, with weak anticholinergic side effects. Rac. -tr-2,3,3a,12b-tetrahydro-2-thioxo-8H-dibenzo (3,4,6,7) cyclohept (1,2-d)oxazol-8-one (5 g), MeOH (25 ml) and Me2NH (25 ml), were refluxed 1 hr. at 63 deg. under N2, evapd., and taken up in 2 NHCl. The soln. was washed (Et2O), basified (NH4OH), the ppt. dissolved in CH2Cl2, the soln. dried, evapd. in vac. and the residue recryst. (MeOH), giving I, m.p 158-9 deg. (Hydrochloride m.p 238-240 deg.). |
| priorityDate | 1967-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 67.