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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-50
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-50
filingDate 1968-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec458564069445db2ef020255506b8cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0eb04a6a6884f56a4f5e9d31f10ab457
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e4d4ba9d28bcf043303182e32d799f71
publicationDate 1970-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-500199-A
titleOfInvention Process for the preparation of 1,3-diazacyclopentene- (2) substituted in the 2-position
abstract Process: (I) R1 = H, lower alkyl, nitrile, trifluoromethyl or pref. halogen X = halogen. (I) are known hypotensives. The process is simple and gives good yields. Compounds which are difficult to prepare using the known isothiuronium salt method are obtained in good yield. Introduction of substituents in ways known for halogenating phenols. The method is esp. quick by reacting compounds or mixtures which develop active halogen in situ such as mixtures of conc. HCl and an oxidising agent such as 30% aqueous H2O2. The new substituents are usually attached at the same posn. as in a corresponding substd. phenol. 2-(2-chloro-4-cyanophenyl)amino-1, 3-diazacyclopentene-(2)-hydrochloride.
priorityDate 1967-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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