http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-499547-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d1845a3df7b600cb98c6ab12e7d28769 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-04 |
filingDate | 1968-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d04b63d2d1ddbafd9ac1fad4eab0360f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c74808f50f96ecedd3352dbd12386fb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afba2e88293001ab9fb7ed367d4bfd8b |
publicationDate | 1970-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CH-499547-A |
titleOfInvention | Process for the preparation of 11-basic substituted dibenzo- (b, f) -1,4-thiazepine-5-oxides |
abstract | Analgesic, sedative, antidepressant and antiemetic 11-piperazinyl-dibenzo-1,4-thiazepine-5-oxides (I) and acid addition salts are prepd. by oxidising the corresp. dibenzo-1,4-thiazepines; R2 = H, allyl, alkyl or alkOH or alkOalk or alkoyloxyalkyl; R2 = NO2, NH2 or SO2NR3R4 (R3, R4, same or different = H, CH3), SOR5 or SO2R5 (R5 = lower alkyl). The thiazepine-oxides where R1 = H may be used for preparing oxides where R1 = allyl, lower alkyl or alkoxy or is not >6 C-alkOalk or alkoyloxyalkyl by reacting the former cpds. with a reactive ester of alcohol R1OH. In an example, an acetic and soln. of 2-nitre-11-(4-methyl-1-piperazinyl)-dibenzo b,f -1,4-thiazepine is oxidised with an aqs. soln. of sodium metaperiodate to the corresp. 5-oxide. |
priorityDate | 1968-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.