http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CH-494768-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d202e9e866984fe229f6facc38f1d740
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-10
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D285-10
filingDate 1967-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_933f65c2051fb55dd84929550283296b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d09b9d574ad70f1fc3472bba87753933
publicationDate 1970-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-494768-A
titleOfInvention Process for the preparation of 4-amino-thiadiazoles
abstract Preparation of compounds of formula: (I) where R = lower alkyl (1-4C), lower alkenyl, or lower alkynyl. Process is according to the following reaction scheme: where M = an alkali or alkaline earth metal Ac = an acyl radical, pref. lower alkanoyl. The reaction is effected as follows: (a) (II) is reacted with an alkylating, alkenylating, or alkynylating agent by conventional means, pref. with a halide in the presence of a weak base, such as an alkali metal carbonate, in an inert solvent. (b) is effected in aqueous or alcoholic media in the presence of a catalytic amount of base, or it may be effected by means of anion exchange resin, e.g. Amberlite IRA-400. (c) is effected by treatment of (IV) with an aqueous alkaline hypohalite (d) is effected by the condensation of (V) with a N-acyl sulphanilyl chloride in the presence of an acid binding agent, such as pyridine. The deacylation stage (e) is effected by conventional acid or base hydrolysis, pref. using 6N HCl. Anticoccidials and antibacterials.
priorityDate 1966-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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