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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 1967-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acf4f4a96357b28cbc567c1a1f2f660b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_710567296e27299e0bce5ae7ad3ef614
publicationDate 1970-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CH-494235-A
titleOfInvention Process for the preparation of 1,2,3,4-tetrahydro-5H-pyrido- (4,3b) -indoles
abstract 2-aroylalkyl-1,2,3,4-tetrahydro-5H-pyrido (4,3b) indoles of general formula (I) ketal derivatives and acid addition salts. Use of (I) as medicants. (where R = chloro, bromo, cyano or trifluoromethyl; R' = O, or ethylenedioxy, R" = H or lower alkyl) Chemotherapeutic agents 1,2,3,4-tetrahydro-5H-pyrido(4,3b) indole unsubstituted in the 2 position is allowed to react with 4-(p-fluorophenyl)-4,4-ethylenedioxy-1-chlorobutane in the presence of an acid acceptor to give (I) (R' = ethylenedioxy) which may then be hydrolyzed (under acidic conditions) to give the corresponding compound where R'=O.
priorityDate 1966-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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