| abstract |
This application relates to an aqueous mixture composition to collect, transport and store samples suspected of containing a pathogen, the composition comprising a chaotropic agent, a chelator, a detergent, a buffer, and optionally an alcohol. The composition inactivates pathogens and stabilizes nucleic acids and proteins contained within a sample and allows downstream extraction and detection assays to proceed without preprocessing. The composition further allows for sample pooling to facilitate high-throughput detection assays. |