| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a02ee55c8ef5a8d909087cb73e104ceb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_449f5be9c64548b15befde3146a7262d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cd7430b93e5a6b98282e2d85372ebf4e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_de03a1db1340a9a68d1b9dd829c9dca9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e54d6839876c29f61d8e98734e5fff8c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c99bf1548f451f2c4bb3202878fd8c76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9d4e5d9ffee59f571fd32d6e30988f13 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2814
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-2835 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6896
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-553 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate |
2020-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccb7bcbf05c35478670ac6a2e3516efd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bce92c6c40cfeed82825b2ce1c2fc462
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f37cece44352862579bf6a53d8c92cad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7edf041b3a55b2df233c878662db413
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c47b7bc6a9aad435e762fe0d0dd2d9e6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3d7008647d3f2de1b1f784727ebef01 |
| publicationDate |
2021-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-3149743-A1 |
| titleOfInvention |
Alpha-synuclein detection using beads |
| abstract |
A method is provided for determining the presence of soluble, misfolded ?-synuclein protein in a biological sample. The method comprises contacting the biological sample with a pre-incubation mixture, the pre-incubation mixture comprising: a monomeric ?-synuclein protein; a buffer composition; a salt; and an indicator, to form an incubation mixture. An incubation cycle is conducted on the incubation mixture in the presence of either a silicon nitride bead or a borosilicate glass bead having a diameter of from about 1 mm to about 5 mm. The method further comprises determining if a detectable amount of misfolded ?-synuclein aggregate is present in the biological sample. |
| priorityDate |
2019-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |