abstract |
The present invention relates to a natriuretic peptide selected from the group consisting of (i) osteocrine, a propeptide of osteocrine or derivative of osteocrine, (ii) a lebetin, a fragment of lebetin or a derivative of lebetin or of a fragment of lebetin, and (iii) an ANP peptide, ANP propeptide or ANP peptide derivative, for use in a method of therapeutic treatment of a bacterial infection associated with a bacterial biofilm in a subject, wherein said natriuretic peptide disperses said bacterial biofilm. In a particular embodiment, said natriuretic peptide is used in combination with an antibiotic. |