Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eee816a5dda012ff9f3650b2ee18cb5e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-04 |
filingDate |
2020-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8fb7698d632bd737dc254faeb8e2705d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8dbbc4d41379edff4f7cd56183e82b56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e60c918fd4d44f3d95e7eaf35ffc0e9d |
publicationDate |
2020-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-3138581-A1 |
titleOfInvention |
Pic1 peptide compositions and methods of use thereof for treatment of hypoxic ischemic encephalopathy |
abstract |
A method of treating hypoxic ischemic encephalopathy (HIE) is described in which a classical complement pathway inhibitor is administered to a neonate. The classical pathway inhibitor can be PIC1, and may have one or more PEG moieties. Treatment of the neonate with the classical complement pathway inhibitor can inhibit inflammation and oxidative damage, such as might arise from ischemia-reperfusion injury. Improvement in fine motor performance, spatial memory and may be achieved. The method may be effective to treat or prevent cerebral palsy. |
priorityDate |
2019-05-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |