http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-3127141-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e2817954cd008bcd609a4c4eb49050be |
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| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-64 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 |
| filingDate | 2019-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4759aecffd4b69c127e8235b277bb1ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0b470e2bc5374b1a1c2a1bad766e3317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c743e49036dae4f43c20461560922ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44f298a52e3089e219da3f4ef6cfe74d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b34c00246b97227d9a3592c08226d1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65a45dfbd1d1778c0008fc2bb2389195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6afb3480fc5d849d437ee8c3b53047f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3cc82ef161eb6538d75de144a78a1cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_613bb77834ed49f5a9a1690412f0034c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9668807934739920a0c671ee09643bfc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a66ee5597bf19648ce3bcca75137452 |
| publicationDate | 2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-3127141-A1 |
| titleOfInvention | Advanced methods for automated high-performance identification of carbohydrates and carbohydrate mixture composition patterns and systems therefore as well as methods for calibrat ion of multi wavelength fluorescence detection systems therefore, based on new fluorescent dyes |
| abstract | The present invention relates to improved (simplified/easier, more robust and more reproducible) methods for identification of carbohydrates compositions, e.g. out of complex carbohydrate mixtures, as well as the determination of carbohydrate mixture composition patterns (e.g.: of glycosylation patterns) based on advanced internal standards to determine precise and highly reproducible migration and retention time indices using novel fluorescent dyes in combination with high performance separation technologies, like capillary (gel) electrophoresis (C(G)E) or (ultra)high performance liquid chromatography (U)HPLC with a highly sensitive detection like (laser induced) fluorescence detection. In a first aspect, the present invention relates to methods for an automated determination and/or identification of carbohydrates and/ or carbohydrate mixture composition pattern profiling as well as a method for an automated carbohydrate mixture composition pattern profiling based on the use of at least a first and second fluorescent label for labelling the migration/retention time alignment standard and sample or different samples, respectively, whereby the at least one of that fluorescent dye is a compound as defined herein. Moreover, the present invention relates to a method for calibration of multi wavelength fluorescence detection systems as well as calibration systems or calibration standards and new compounds suitable for calibration are described. The present invention relates further to a kit or system for determining or identifying carbohydrate mixture composition patterns as well as a kit or system for determining and/or identifying carbohydrate mixture composition pattern. Further, a carbohydrate dye conjugate comprising the dye as defined herein for use in a method according to the present invention is provided. The dyes employed for forming the carbohydrate dye conjugate have formula A or B below: |
| priorityDate | 2019-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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