| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c1407305b111544dbf55c3eebbdf89e |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-06013
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2881
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate |
2019-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b54f9bc6eb84cbd35f95cc4e5c457b0e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3c3b6549722c7d5e50c8c54f7fbe5ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d80a7a318a447aa5a3e65a7f07cfb48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_356baf7613c48ef8ad64dcb7dca85783
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e74d0f78fe39bba6547cd6f871ed2ec5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eabb71f7d3e4cb4978c2c1484299d155
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_289a3b0bd945769757010aaaff6632f4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9dc147e9bcbd348d209d544107f548e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7787e430ec7eda61b62bcbfa86726cd4 |
| publicationDate |
2020-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-3121927-A1 |
| titleOfInvention |
Lysosomal storage disorder biomarkers and methods of use thereof |
| abstract |
Certain embodiments provide a method of detecting one or more biomarkers in a subject having a lysosomal storage disorder, the method comprising: 1) measuring the concentration of a combination of two or more lipids in a sample from the subject, wherein the combination of lipids is selected from the group consisting of: a) a bis(monoacylglycero)phosphate (BMP); b) a GM2 ganglioside and/or a GM3 ganglioside; c) a GD3 ganglioside; d) a GD1a/b ganglioside; and e) a glucosylceramide (GlcCer); 2) measuring the concentration of GlcCer in a sample from the subject; 3) measuring the concentration of neurofilament light chain (Nf-L) in a sample from the subject; and/or 4) measuring the concentration of soluble triggering receptor expressed on myeloid cells 2 (sTREM2) in a sample from the subject. |
| priorityDate |
2018-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |