| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b0415d6923e2f80c6c8872becb568967 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1093
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1096
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K51-1027 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-44 |
| filingDate |
2019-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2df060e9e9c6319480bd1d298d7d4b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_745d2651318338a4ea2d5ff494872b28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_502349a5a2fafe2b8be6ae0e6c9482cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_adfc8098dcdae4fd36478cd5bda600de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0eaed019d0a45be5a498f20432745ffd |
| publicationDate |
2020-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-3121553-A1 |
| titleOfInvention |
Antibodies conjugated with actinium-225 and actinium-227, and related compositions and methods |
| abstract |
This invention provides a compositions of matter comprising a therapeutic protein population (such as a HuM195 antibody population) wherein (a) each therapeutic protein in the population is conjugated to one or more actinium atoms, (b) each actinium atom is either 227Ac or 225Ac, and (c) the molar ratio of 227Ac to 225Ac in the composition is at least 1:1, This invention also provides related synthetic compositions and methods, as well as methods for treating hematologic malignancies. |
| priorityDate |
2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |