abstract |
The present invention relates to methods for regenerating nervous system tissue or treating a neurological disorder by administration of a therapeutically effective amount of synthetic tissue containing a cell population of one or more nervous system cell types (e.g., neurons) or multipotent cells (e.g., mesenchymal stem cells), where the cell population is embedded within a modular synthetic hydrogel that is biocompatible. In some preferred embodiments the modular synthetic hydrogel includes a PEG hydrogel crosslinked with a glycosaminoglycan such as hyaluronan. |