| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8dde94dce60e96fd9e7426f319f4d158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9916a6e9066d97f64b89bd309b48d1a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1db377f3d056249b596df7893ebb54d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-392
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-125
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1358
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-566
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-28 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0789 |
| filingDate |
2019-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2b2649fee6f24c3a148a5c5d7e74097
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9b145bd3ba6b732b790e0e68e95ef43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f191d07a020d70a29c48dc0713eca7a2 |
| publicationDate |
2020-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-3117581-A1 |
| titleOfInvention |
Improvements for performing and facilitating the recovery after hematopoietic stem cell transplantation |
| abstract |
The present invention provides a method to enhance hematopoietic reconstitution and recovery after hematopoietic stem cell transplantation which is based on the administration of estetrol to the subject that has undergone the transplantation, because estetrol induced an increment in the percentage of hematopoietic cells derived from transplanted donor cells in the recipient. Additionally, estetrol increase the donor contribution in the hematopoietic stem cell compartment. A method for increasing the number of hematopoietic progenitor or stem cells in a culture is also provided, based as well in the addition of estetrol to the culture. As the obtained hematopoietic progenitor or stem cells can be also transplanted, the method increases the availability of donor cells for transplantation. Thus, the invention improves hematopoietic stem cell transplantation in patients. |
| priorityDate |
2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |