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filingDate 2019-10-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-3112640-A1
titleOfInvention Genetically modified salmon which produce sterile offspring
abstract The present invention relates, inter alia, to a process for making modified fish zygotes or early- stage fish embryos (particularly salmon zygotes and salmon embryos), wherein the process comprises (a) modifying the genome of the fish zygote or an early-stage fish embryo to eliminate functional expression of a germ cell survival factor gene (e.g. dead-end, dnd)\ and (b) introducing functional protein or RNA encoded by the germ cell survival factor gene into the zygote or early-stage embryo. The invention also provides fish zygotes, fish embryos, juvenile fish, mature fish and sterile fish which are produced by the processes of the invention.
priorityDate 2018-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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