| abstract |
Abstract The invention relates to benzimidazoles of Formula (I) R4 R3 -)r0 R3 R2 H-R5 R6 )CH3 R1 and pharmaceutically acceptable salts thereof, wherein R1 to R6 are as defined in the description; to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The benzimidazoles of Formula (I) are ITK inhibitors and are therefore potentially useful in the treatment of a wide range of disorders including, atopic dermatitis. Date Recue/Date Received 2020-12-17 |