abstract |
A G1T38 human oral dosage regime that provides a (mean AUC(0-24),ss (h*ng/mL)) / (dose (mg)) ratio of less than 5 and/or a (mean AUC(0-24),ss (h*ng/mL)) / (Absolute Neutrophil Count (cells/mm3)) ratio on day 22 of closing of not greater than 1.25. |