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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-807
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B32-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02
filingDate 2012-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1731c4e674cf9fe21ab761b7b1e1f831
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87c28d2e13fba6ad7a62660bdfe76386
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e79d59ac98271425d2dd8d58e9c27c44
publicationDate 2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-3085614-C
titleOfInvention Methods of isolating (4-chloro-2-fluoro-3-substituted-phenyl)boronates and methods of using the same
abstract 86413668 ABSTRACT Methods of isolating a 4-chloro-2-fluoro-3-substituted-phenylboronate include adding carbon dioxide gas or carbon dioxide solid (dry ice) to a solution comprising a 4-chloro-2-fluoro-3-substituted-phenylboronate, an inert organic solvent, and at least one lithium salt to react the at least one lithium salt with the carbon dioxide gas or carbon dioxide solid (dry ice) and fonn a mixture comprising the 4-chloro-2-fluoro-3- substituted- phenylboronate, the inert organic solvent, and a precipitated solid. The precipitated solid may be removed from the mixture. Methods of using 4-chloro-2-fluoro-3-substituted- phenylboronates to produce methy1-4-amino-3-chloro-6-(4-chloro-2-fluoro-3- substituted- phenyl)pyridine-2-carboxylates are also disclosed. A 4-chloro-2-fluoro-3- substituted- phenylboronate produced by one of the methods of isolating a 4-chloro-2-fluoro- 3- substituted-phenylboronate is also disclosed, wherein the 4-chloro-2-fluoro-3- substituted- phenylboronate may be obtained at a yield of greater than or equal to about 90%. Date Recue/Date Received 2020-07-06
priorityDate 2011-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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