Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15d42f684941d5b0617ca7764ebdff07 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2030-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2750-14151 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N30-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-861 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-864 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-00 |
filingDate |
2010-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_833479b1525a79040808a795a0ee27c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86b3193864f46d4d5d5a0d5a468d3cec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_79c6eb51725056ac3f47da6781eaaf10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b19f6a75260e87bbfbb6602e2a1de703 |
publicationDate |
2022-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-3077531-C |
titleOfInvention |
Improved methods for purification of recombinant aav vectors |
abstract |
Provided herein are methods for isolating populations of recombinant adeno-associated virus (rAAV) particles involving contacting rAAV particles with a hydrophobic interaction chromatography (HIC) medium in a high salt buffer. The isolated populations of rAAV particles may be used for gene transfer and specifically for gene therapy or vaccination. rAAV particles of the invention are substantially free of in-process impurities, including production components such as cellular nucleic acids, cellular proteins, helper virus, and media components. |
priorityDate |
2009-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |