abstract |
There is provided a cosmetic composition comprising: a polyphenolic antioxidant agent; and a sphingosine compound of Formula (I), or a salt thereof, in which the sphingosine compound is present at about 10 to about 100 times the amount of the polyphenolic antioxidant agent, by weight. The described cosmetic compositions can be applied topically and are useful in inhibiting interleukin-6. The described cosmetic compositions provide improved skin responsiveness to, and/or protection against, exogenous and endogenous insults, including pollution insult. (I) |