Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a9a66b0bf1cce655ea85ad7221bba215 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-21 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-07006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1252 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1247 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2018-01-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbc2e0ebe9c45e6047977837a33ca648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a26b1f0eee6f24d13c6f826af7a6988b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bfebe546744c5e5ffd24498169492ac http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23ea1d388173508a8070016ea65469f3 |
publicationDate |
2023-01-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-3049722-C |
titleOfInvention |
Polymerases engineered to reduce nucleotide-independent dna binding |
abstract |
Provided are engineered DNA polymerases exhibiting modified functionality, and polynucleotides encoding same. Modified features include: (1) reduced catalytic activity in the presence of magnesium ions and/or (2) reduced affinity for primed template nucleic acid molecules in the absence of cognate nucleotide, and an ability to discriminate between cognate and non-cognate nucleotides under low salt conditions. Sequencing By BindingTM procedures employing the engineered polymerases have certain advantages. The engineered polymerases can have other uses as well. |
priorityDate |
2017-01-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |