http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-3046578-A1

Outgoing Links

Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d01227a7111c7565c8a5a1906a182c9
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00
filingDate 2017-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cdb8925d05daf09333ca7e708498f60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06509ed9a1a7ee29dee897c2ad1a4fe2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_59418f136a07ada64117306bb90666d4
publicationDate 2018-06-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-3046578-A1
titleOfInvention Imidazopyrazine inhibitors of bruton's tyrosine kinase
abstract In some embodiments, the invention relates to the compounds of Formula (I) and (II) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, in some embodiments, the present invention relates to the compounds of Formula (I) and (II), pharmaceutical compositions thereof, and the use of the compounds and pharmaceutical compositions in the treatment of a hyperproliferative disorder, an inflammatory disorder, an immune disorder, or an autoimmune disorder.
priorityDate 2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

Predicate Subject
isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID107987479
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID28474
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16453
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102117212
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID2725057
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID403588
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID282211
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP07943
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID71310626
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID280675
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID364403
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3874950
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP02248
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HKG6
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID10407
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID29183
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID31564
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID36203
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5HJP2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100192952
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID10566
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100995695
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID416477
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP22570
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID850620
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12143
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100385343
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID378424
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO35815
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID695
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1559
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP15121
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID553615
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID465759
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID494129
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID430135846
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID367901
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID68205
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1565
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11103
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID503552
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID110616
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP24338
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP04838
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP99120
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5621
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID14149
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP62975
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100007677
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID735881
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1564
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID386966
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8ID50
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID16428
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100976899
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3718
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24337
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID798906
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102130662
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100009122
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP68197
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID14654
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID410950281
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8SWD4
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID737737
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8SSK6
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID504509
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID238428
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP19848
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396407
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID31398
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9W689
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID368667
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID430703115
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID101825565
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135370767
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID367
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6GCZ8
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID14924508
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100799042
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2741
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP80276
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25326
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID68535
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11997
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID461343
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16116
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID14187
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID505709
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100689318
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP08165
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID22637
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7006
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP15122
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID25674
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33629
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9V3T9
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100124696
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID492019
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID414841
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID414856
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP54252
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID24750
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP21300
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID19122
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID561370
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID79122
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID374075
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID326237
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2232
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID532587
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID692587
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP45376
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11677
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID317748
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID567764
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID34132
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100910768
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2066
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP84589
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID5753
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID747460
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO08782
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID216818
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID470228
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID493887
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID568653
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID422165
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID494010
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID640
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396051
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP38715
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID301348
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69313
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69310
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426204645
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID374
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9CVD2
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69326
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID858590
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP45377
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID411478303
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13077
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2064
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69317
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP82861
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID78988658
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID2725057
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ04520
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID463582
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID366275
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID231
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID610004
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419551196
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID59323
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13075
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID396816
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID21682
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6GKH9
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID529814
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419517651
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID433322161
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID84492
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100616515
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24208
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID171522
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID533459
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12124
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102144258
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24192
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID12229
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID451339314
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID414611032
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13869
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ61578
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID71226662
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1558
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID154496479
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1557
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID415122
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100360645
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID482140
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11839
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID101256912
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID414746
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID176718
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID4287
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID135177661
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10376
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID11103
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID571588
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6474107
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP31955
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ54KG7
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID13866
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419529444
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID11835
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID2541030
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID10439
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID378754
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP23901
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24297
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP48360
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ865C5
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100062244
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10407
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1544
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID60331
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID38456
http://rdf.ncbi.nlm.nih.gov/pubchem/taxonomy/TAXID10566
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID421153761
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID6059187
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100062285
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453224783
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID426096638
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID44503
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP56522
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID10376
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP15514
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100404344
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419531505
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID20459
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP66776
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID101829062
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8CQD2
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100499575
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID13450755
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP66775
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID33432
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID7535
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID18124
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ48436
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO59710
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID467151
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID3702
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID34420
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID100005148
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID1576
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID24303

Total number of triples: 258.