| abstract |
The present invention relates to an oral hemostatic and wound-protective film which can be attached to a cut portion in an oral cavity so as to delay or prevent microbleeding and to control release of medicinal ingredients. The present invention comprises polyol, alcohol and a biodegradable polymer in a partly swollen state, thereby being capable of absorbing blood or abscesses in a topical region and stopping bleeding. Further, as the film of the present invention has a large elongation rate , it is possible to maintain an adhesive force after absorbing blood, saliva and abscesses in an oral cavity. In addition, as the film easily transforms to a topical site with curvatures, the film is less irritating even when attached to such a topical site for a long time. Further, as the film of the present invention comprises a disintegrating agent which is dissolved and released when reacting with blood to form microchannels serving as a drug release passage, it is possible to control a drug release amount by controlling the amount and size of the microchannels. Since an adhesive layer and a support layer of the present invention are dissolved and removed over time, a patient does not have to detach a transporter film attached in the oral cavity by hand . |