Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d62d92aaf868f7c4e0a1c6445ca2a3c1 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G2230-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-183 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-0241 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6935 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1273 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G64-081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6835 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G64-30 |
filingDate |
2016-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9dda852bf1a18969afa55c432c2d0341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2ff223b97dba1e3a8c85e5f28bf585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_115560b53c7b976cb72c9e041c91b22b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04b2a56d31389eeeda862dcb046f1963 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84c61ecaecb08638e93c91d56fc06fb9 |
publicationDate |
2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-3009252-C |
titleOfInvention |
Biodegradable amphiphilic polymer, polymeric vesicles prepared therefrom, and application of biodegradable amphiphilic polymer in preparation of medicines for targeted therapy of lung cancer |
abstract |
Disclosed is a polymeric vesicle prepared by a biodegradable amphiphilic polymer, and the polymeric vesicle for use as a carrier of a drug for lung cancer treatment , wherein the chemical structure of the biodegradable amphiphilic polymer is one of the following structures: (see formula I) (see formula II) The biodegradable amphiphilic polymer is obtained by an activity-controllable ring-opening polymerization based on a cyclic carbonate monomer containing a functional group of dithiolane ring, which has a controllable molecular weight and a narrow molecular weight distribution; the polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer of the present disclosure has biodegradability and can be used to control the drug release system, the prepared lung cancer-targeted reduction-sensitive reversibly-crosslinked polymeric vesicle as a nanomedicine carrier supports stable long circulation in vivo. |
priorityDate |
2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |