http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2967876-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-18 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 |
filingDate | 2015-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afdcd12810182d10c345c5272db8a219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9eae79b56033b7fd8191203780a63c9 |
publicationDate | 2016-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CA-2967876-A1 |
titleOfInvention | Formulations comprising a meglumine salt of the metal complex gd-dota |
abstract | The present invention relates to a method of preparation of formulations of gadolinium metal complexes of the macrocyclic chelator DOTA as a meglumine salt, which further comprise a small excess of free DOTA. The method uses controlled conditions such that excess gadolinium is present as a precipitate of gadolinium oxide, with filtration to remove the excess, prior to the addition of a defined excess of DOTA chelator. Also provided is a method of preparation ofMRI contrast agents based on Gd-DOTA. |
priorityDate | 2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.