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publicationDate 2016-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2956696-A1
titleOfInvention Noninvasive body fluid stress sensing
abstract Electrochemical impedance-based label-free and rapid biosensor for select bodily fluid biomolecule levels. Monoclonal antibodies to of biomolecule such as Cortisol were covalently attached to a 16-mercaptohexadecanoic acid functionalized gold working electrode using zero-length crosslinkers N-(3-dimethylaminopropyl)-N- ethylcarbodiimide and 10mM N-hydroxysulfosuccinimide. Cortisol was detected in phosphate buffered saline (simulated tear fluid) using a simple ferrocyanide reagent with a lower limit of detection of 18.73pM and less than 10% relative standard deviation.
priorityDate 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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