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filingDate 2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8aeedfa0a1f4215768a8d71cf209dd01
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publicationDate 2015-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2949545-A1
titleOfInvention Methods of treating and preventing vascular instability diseases
abstract Methods are disclosed for treating and preventing vascular instability diseases, such as cerebral cavernous malformation, by the administration of tempol, cholecalciferol, derivatives thereof, pharmaceutically-acceptable salts thereof, or combinations thereof. Methods are disclosed for reducing the number of cerebral cavernous malformation (CCM) lesions in a patient having, or at risk of developing, at least one CCM lesion. Methods are disclosed for reducing the growth rate of the number of cerebral cavernous malformation (CCM) lesions in a patient having, or at risk of developing, at least one CCM lesion. Method are disclosed for preventing or treating a sign or symptom of cerebral cavernous malformation (CCM) in a patient with at least one CCM lesion. Methods are disclosed for decreasing cerebrovascular inflammation, reducing cerebrovascular permeability, or both, in a patient having, or at risk of developing, a cerebral cavernous malformation (CCM) lesion. Methods are disclosed for improving cerebrovascular health in a patient having, or at risk of developing, a cerebral cavernous malformation (CCM) lesion.
priorityDate 2014-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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