http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2941784-A1

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c8360e82acdb5ebd5bbb709914a4a600
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1068
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10
filingDate 2015-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e6efef62cfd1d6d678ac2f29f0d438e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a16abff6c7a46c75584caede445e5b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd5f7e5a5f9260ee8d3dd2911701e27
publicationDate 2015-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2941784-A1
titleOfInvention Purification of dna-conjugate products
abstract This invention relates to the purification of nucleic acid conjugates, for example for use in DNA encoded chemical libraries. Reaction members that comprise nucleic acid conjugate reaction products and nucleic acid or nucleic acid conjugate reactants comprising a first reactive group are contacted with a capping molecule comprising a capture group. The capping molecule reacts with the first reactive group to form a covalent bond, thereby attaching the capture group to nucleic acid or nucleic acid conjugate reactants in reaction members. The nucleic acid or nucleic acid conjugate reactants are then removed from the reaction members using a binding member that binds the capture group, thereby producing a purified population of nucleic acid conjugate products. Methods of producing purified populations of nucleic acid conjugate products and nucleic acid chemical libraries are provided along with chemical libraries and kits.
priorityDate 2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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