abstract |
The present invention relates to substituted 4,5,6,7-tetrahydro-pyrazolo[1,5-c]pyrimidine derivatives and 2,3-di-hydro-1H-imidazo[1,2-b]pyrazole derivatives of formula (I) and also compounds of fommla (1'). The compounds according to the present invention are useful as ROS1 inhibitors. The invention further relates to processes for preparing such novel compounds, phamiaceutical compositions comprising said compounds as an active ingredient as well as the use of said compounds as a medicament. (11") |