abstract |
The present invention relates to a class G immunoglobulin directed against the anthrax protective antigen (PA), or a fragment thereof, comprising at least: a heavy chain variable region comprising an amino acid sequence represented with the sequence SEQ ID NO: 1, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 1, and comprising the amino acids Leucine at position 51 and Glycine at position 67, and a light chain variable region comprising an amino acid sequence represented by the sequence SEQ ID NO: 2, or comprising an amino acid sequence having at least 90% identity with the sequence SEQ ID NO: 2, and comprising Leucine amino acid at position 55. The invention also relates to uses of such an immunoglobulin. |