Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8828412a08c427cf0e753b98d7339754 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-363 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37 |
filingDate |
2015-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a512e8b347f510da20430f167822da07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_af11b5dc148d96da2ecbcfab96d6ac01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df02b9a8475d0f3672f9c6ea7f6560b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4506e30eb1e80d45dc13eba23a4fd1ee |
publicationDate |
2015-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2934705-A1 |
titleOfInvention |
A process for manufacturing factor viii having an improved ratio of fviii:c/fviii:ag |
abstract |
A process for manufacturing of a Factor VIII product having a ratio of FVIII :C/FVIII :Ag of at least 0.7 in the Factor VIII product by using chromatography wherein at least one chromatographic step is performed by means of employing; An affinity chromatography resin having an affinity for specifically binding of Factor VIII which is effected by an affinity ligand which is immobilised on the affinity chromatography resin, said affinity ligand is a 13 kD yeast derived Fab antibody fragment directed to the Factor VIII molecule. An anionic chromatography resin. A size exclusion resin. A Factor VIII product obtainable according to the process with a monomer content of >98 % for treatment of haemophilia and avoiding formation of inhibitors. |
priorityDate |
2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |