| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6645ce16dbbcebca4cd8d594d264e9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e62898e7789eacc784f239af0e1ccea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b08fd5336ec3dd22e427176de8f588a2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16043
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N63-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate |
2014-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fe239295bb35be6a1fe762e3ac771f2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43fba8df3fe44e54076d7c4ca314c040
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98d9718451aaa89850157d2683730a09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_626ea690003ee1f8ead32828ef99649d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18e165a2a696bb59f6df778b19154b87 |
| publicationDate |
2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2926078-A1 |
| titleOfInvention |
Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells |
| abstract |
Disclosed are ex vivo methods for targeted integration into purified hematopoietic stem cells (HSC) and/or progenitor cells (PC). Selected embodiments provide for delivering a non-integrating lentiviral (IDLV) donor nucleic acid to the cells, and culturing the cells prior to delivering at least one zinc finger nuclease to the cells so that the donor nucleic acid is integrated into the target genome. This in turn provides advances in the field of genome engineering, particularly targeted modified of a hematopoietic cell. |
| priorityDate |
2013-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |