http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2920080-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_277c3695533f5075b05990f25f65462f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-22 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-22 |
| filingDate | 2014-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d109acdb81b62c919ad3341b0eb9d4a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41b52a1c81582dd47710afc014e4f2c0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da49fd0207c4a44ad4b595f1fa6ab23f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b127525d007442de228ef74663c413c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8b11008a825a9f2b487c88a4d76fc19 |
| publicationDate | 2015-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2920080-A1 |
| titleOfInvention | A process for preparing rifaximin .kappa. |
| abstract | The present invention relates to a process for obtaining rifaximin ? comprising the following steps:a) reacting rifamycin O with 2-amino-4-picoline in the presence of a solvent mixture comprising water and a solvent selected from methyl isobutylketone, ethylacetate and a water soluble solvent; b) obtaining a rifaximin solution by removing the aqueous phase; c) obtaining rifaximin ? from the rifaximin solution, wherein when the solvent is a water soluble solvent, either methyl isobutylketone or ethylacetate is further added in step a). In another aspect the process of the invention relates to a process for obtaining the crystalline form ? of rifaximin comprising the following steps: i) contacting rifaximin or a rifaximin solution with exclusively ethylacetate, ii) obtaining the rifaximin in crystalline form ? by removing ethylacetate. |
| priorityDate | 2013-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.