abstract |
A method and composition for treating a host infected with flavivirus or pestivirus comprising administering an effective flavivirus or pestivirus treatment amount of a 1', 2' or 3'-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided, wherein the nucleoside is a .beta.-D-2'-C-methyl-3'-OH-4'-H-5'-OH-uracil ribonucleoside or 5'-triphosphate therefor a .beta.-D-2'-C-methyl-3'-OH-4'-H-5' -OH-cytosine ribonucleoside or triphosphate thereof. |