Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7d241434dd2e686fcc5aab7061164f8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8381805eba6d034fc77bd230dd02e6e2 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4833 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5036 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J13-046 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
filingDate |
2014-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bd07534dcf356544c91d901e80cf31e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2aa14306b532253e165217d370709ab6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec9f64de2019d5dbc04ea70eb0b6edbf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98a7c8b67044e65f3b65d81b9d161cdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8175a91f48db86e1996f492634fb984 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_279f4fada833cbf7113307cbb873a8fa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec98578d1bb124837009c73b0be25117 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3db36d0eaa60d1d2076bb52cc18fa750 |
publicationDate |
2014-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2906174-A1 |
titleOfInvention |
Multi-layer hydrogel capsules for encapsulation of cells and cell aggregates |
abstract |
Biomedical devices for implantation with decreased pericapsular fibrotic overgrowth are disclosed. The device includes biocompatible materials and has specific characteristics that allow the device to elicit less of a fibrotic reaction after implantation than the same device lacking one or more of these characteristic that are present on the device. Biocompatible hydrogel capsules encapsulating mammalian cells having a diameter of greater than 1 mm, and optionally a cell free core, are disclosed which have reduced fibrotic overgrowth after implantation in a subject. Methods of treating a disease in a subject are also disclosed that involve administering a therapeutically effective amount of the disclosed encapsulated cells to the subject. |
priorityDate |
2013-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |