http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CA-2902624-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28e3113097dd6d28720572e47f2f2407 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-71 |
| filingDate | 2014-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffab960a248cc4ac9e9c4028decd089d |
| publicationDate | 2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CA-2902624-A1 |
| titleOfInvention | Method for producing sulfonyl chloride compound |
| abstract | The purpose of the present invention is to provide a method for producing an intermediate which can be used in a method for producing a sulfonylpyrrole compound that is useful as a medicine. The present invention relates to a method for producing a sulfonylpyrrole compound (VI), said method comprising: reacting a pyridine-3-sulfonic acid compound with phosphorus pentachloride in a solvent that is chlorobenzene or trifluoromethylbenzene to produce a pyridine-3-sulfonyl chloride compound; then reacting the pyridine-3-sulfonyl chloride compound with a compound (III) without isolating the pyridine-3-sulfonyl chloride compound to produce a compound (IV); and then subjecting the compound (IV) to a reductive amination reaction to produce the sulfonylpyrrole compound (VI). (In formula (III), R2 represents a hydrocarbon group or the like; and R3 and R4 independently represent a hydrogen atom or the like.) (In formula (IV), R1 represents a pyridin-3-yl group which may be substituted; and other symbols are as defined above.) (In formula (VI), R5 represents an alkyl group; and other symbols are as defined above.) |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I702211-B |
| priorityDate | 2013-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 652.