Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2503-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-45 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-46 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
filingDate |
2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_024b6a6d6a7d87bb6c47d9f4f08ff0c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61d63bc7cce2ab43814a40e6ee5d3f41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6cdc83c3c3133a5d64206f85eab920d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be130956655882e224a3ae5e0441c68c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9784829be91c057b79ca40ef58772724 |
publicationDate |
2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CA-2900690-A1 |
titleOfInvention |
Compounds for improved stem cell differentiation into hepatocytes |
abstract |
The invention relates to the compounds of formula I and pharmaceutically acceptable salts and esters thereof, wherein R 1-R 11are as defined in the description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are useful in differentiating stem cells into more mature or adult-like hepatocytes for use as drug screening platforms and in disease modeling applications. |
priorityDate |
2013-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |