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filingDate 2015-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97d2ab2d699b7bb52bf714d3f98ba50a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc857c67f79504c89645ace6de81c495
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publicationDate 2017-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CA-2897389-A1
titleOfInvention Dual targeting antisense oligonucleotides as apoptotic inhibtor therapeutic compostions and methods for their use in the treatment of cancer
abstract Provided herein are compositions, method and uses for modulating IAP activity or for the treatment of cancer. The compositions comprise dual-targeting antisense oligonucleotides (dASO) for administration to a cancer cell, wherein the cancer cell may be characterized by elevated expression of one of more of BIRC6, cIAP1 or survivin. The cancer may be selected from one or more of: prostate cancer; childhood de novo acute myeloid leukemia; colorectal cancer; neuroblastoma; melanoma; and non-small cell lung cancer. The prostate cancer may be castration-resistant prostate cancer (CRPC).
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http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018129622-A1
priorityDate 2015-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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