| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e9bca1120ab9d2f65b138f53e3eda4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2510-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-405
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-115
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2501-11 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0623 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0797
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-86
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-30 |
| filingDate |
2011-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da79033f295d32cd6b40870253c5d2eb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ec031531839c62ca54d4dec5ac7cc9ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca27007a02a26f18cba61ac95cc2f850
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6efa2150d66c01b41d6fd3d900e244b7 |
| publicationDate |
2019-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CA-2883922-C |
| titleOfInvention |
Method for proliferating stem cells by activating notch signaling |
| abstract |
The present invention relates to stem cells in which a gene that activates signaling is introduced and to a method for proliferating the stem cells. More specifically, the invention relates to a method of significantly increasing the ability of stem cells to proliferate by transfecting stem cells with the Notch intracellular domain (NICD) to activate the Notch signaling pathway. According to the present invention, as a result of activating the Notch signaling pathway, stern cells having an excellent ability to proliferate can be produced in large amounts. Particularly, since neural stem cells which have been difficult to culture in vitro can be proliferated in large amounts, thus the neural stem cells will be more useful for the preparation of cell therapeutic agents for treating cranial nerve diseases. |
| priorityDate |
2010-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |